Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26729524 | 0.80 | TSHR (0.46) | MAOBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL24302324 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL24939760 | 0.77 | CA12 (0.44) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL23117415 | 0.76 | MAPT (0.51) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL23117302 | 0.75 | KDM4E (0.47) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL25603244 | 0.74 | MAPT (0.43) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL31323471 | 0.74 | MAPT (0.43) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL24754290 | 0.74 | MAPT (0.43) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL23117602 | 0.74 | HPGD (0.47) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL24302315 | 0.73 | MAPT (0.41) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262782-A1 | GLUTARIMIDE-SUBSTITUTED ISOXAZOLE FUSED RING COMPOUND, AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2022-12-22 | — | — | WO | disclosed |