Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1065002 | 0.84 | MEN1 (0.69) | MEN1KMT2AHDAC1HDAC7KDM4E | |
| SCHEMBL2019296 | 0.83 | MEN1 (0.67) | MEN1KMT2AHDAC1HDAC7KDM4E | |
| SCHEMBL30414177 | 0.80 | MEN1 (0.48) | MEN1KMT2AHDAC1HDAC7KCNH2 | |
| SCHEMBL25204255 | 0.80 | MEN1 (0.48) | MEN1KMT2AHDAC1HDAC7KCNH2 | |
| SCHEMBL31667008 | 0.79 | KMT2A (0.62) | MEN1KMT2AHDAC1HDAC7KDM4E | |
| SCHEMBL2024836 | 0.79 | KMT2A (0.66) | MEN1KMT2AHDAC1HDAC7KDM4E | |
| SCHEMBL27991792 | 0.79 | KMT2A (0.62) | MEN1KMT2AHDAC1HDAC7KDM4E | |
| SCHEMBL1466305 | 0.79 | KMT2A (0.60) | MEN1KMT2AHDAC1HDAC7KDM4E | |
| SCHEMBL29630944 | 0.79 | KMT2A (0.60) | MEN1KMT2AHDAC1HDAC7KDM4E | |
| SCHEMBL3707181 | 0.79 | MEN1 (0.62) | MEN1KMT2AHDAC1HDAC7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022263829-A1 | COMPOUNDS AND THEIR USE FOR THE TREATMENT OF α1-ANTITRYPSIN DEFICIENCY | Z Factor Limited (GB) | 2022-12-22 | — | — | WO | disclosed |