Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 14/20 | 0.73 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.61 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20721180 | 0.84 | CCR6 (1.00) | CCR6 | |
| SCHEMBL20721179 | 0.84 | CCR6 (1.00) | CCR6 | |
| SCHEMBL20721281 | 0.82 | CCR6 (1.00) | CCR6CXCR2CXCR1 | |
| SCHEMBL12262467 | 0.82 | CCR6 (1.00) | CCR6CXCR2CXCR1 | |
| SCHEMBL12087174 | 0.82 | CCR6 (1.00) | CCR6CXCR2CXCR1 | |
| SCHEMBL20721136 | 0.82 | CCR6 (1.00) | CCR6 | |
| SCHEMBL24755261 | 0.81 | CCR6 (0.74) | CCR6CXCR2CXCR1 | |
| SCHEMBL13479448 | 0.79 | CCR6 (0.78) | CCR6CXCR2 | |
| SCHEMBL12262523 | 0.76 | CXCR2 (1.00) | CCR6CXCR2CXCR1 | |
| SCHEMBL20761373 | 0.73 | CCR6 (0.71) | CCR6CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402866-A1 | 3,4-DISUBSTITUTED 3-CYCLOBUTENE-1,2-DIONES AND USE THEREOF | ALLERGAN, INC. | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402866-A1 | 3,4-DISUBSTITUTED 3-CYCLOBUTENE-1,2-DIONES AND USE THEREOF | IL17A, TSLP, SSB | CCR6 197/4885CXCR2 303/4885CXCR1 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.