Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | NMBR | P28336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475588 | 1.00 | SIRT2 (0.53) | SIRT2HCRTR1MAPTPOLBTDP1 | |
| SCHEMBL2472734 | 0.93 | SIRT2 (0.53) | SIRT2HCRTR1MAPTPOLBTDP1 | |
| SCHEMBL2472735 | 0.93 | SIRT2 (0.53) | SIRT2HCRTR1MAPTPOLBTDP1 | |
| SCHEMBL2477239 | 0.92 | SIRT2 (0.61) | SIRT2NMBR | |
| SCHEMBL2476426 | 0.92 | SIRT2 (0.61) | SIRT2NMBR | |
| SCHEMBL2476422 | 0.92 | SIRT2 (0.61) | SIRT2NMBR | |
| SCHEMBL2469722 | 0.91 | SIRT2 (0.51) | SIRT2MAPTPOLBTDP1MAOA | |
| SCHEMBL2469716 | 0.91 | SIRT2 (0.51) | SIRT2MAPTPOLBTDP1MAOA | |
| SCHEMBL2472238 | 0.88 | SIRT2 (0.57) | SIRT2NMBR | |
| SCHEMBL2472234 | 0.88 | SIRT2 (0.57) | SIRT2NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371421-A1 | Ligands of insulin degrading enzyme and their uses | Université de Lille 2 Droit et Santé (FR) | 2011-10-05 | — | — | EP | disclosed |