Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | NMBR | P28336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476426 | 1.00 | SIRT2 (0.61) | SIRT2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2476422 | 1.00 | SIRT2 (0.61) | SIRT2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2476116 | 0.95 | SIRT2 (0.56) | SIRT2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2476117 | 0.95 | SIRT2 (0.56) | SIRT2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2473478 | 0.95 | SIRT2 (0.58) | SIRT2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2473482 | 0.95 | SIRT2 (0.58) | SIRT2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2472238 | 0.94 | SIRT2 (0.57) | SIRT2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2472234 | 0.94 | SIRT2 (0.57) | SIRT2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2475588 | 0.92 | SIRT2 (0.53) | SIRT2NMBR | |
| SCHEMBL2475599 | 0.92 | SIRT2 (0.53) | SIRT2NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371421-A1 | Ligands of insulin degrading enzyme and their uses | Université de Lille 2 Droit et Santé (FR) | 2011-10-05 | — | — | EP | disclosed |
| WO-2011107948-A2 | LIGANDS OF INSULIN DEGRADING ENZYME AND THEIR USES | UNIVERSITE LILLE 2 DROIT ET SANTE (FR) | 2011-09-09 | — | — | WO | disclosed |