⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14227908 | 0.93 | — | — | |
| SCHEMBL7274011 | 0.76 | — | — | |
| SCHEMBL16765733 | 0.73 | — | — | |
| SCHEMBL283488 | 0.71 | — | — | |
| SCHEMBL6472812 | 0.71 | — | — | |
| SCHEMBL2977209 | 0.71 | — | — | |
| SCHEMBL10867079 | 0.71 | SPHK2 (0.45) | — | |
| SCHEMBL25262256 | 0.71 | CYP1A2 (0.55) | — | |
| SCHEMBL4680796 | 0.71 | — | — | |
| SCHEMBL6504099 | 0.71 | L3MBTL1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402904-A1 | 3-(5-methoxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione Derivatives and Uses thereof | NOVARTIS AG (CH) | 2022-12-22 | — | — | US | disclosed |