Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HK1 | P19367 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24760551 | 1.00 | KDM4E (0.44) | KDM4EHPGDSLC6A2MAPTHK1 | |
| SCHEMBL24760552 | 0.91 | SLC6A2 (0.38) | KDM4ESLC6A2MAPTHK1HKDC1 | |
| SCHEMBL24761866 | 0.91 | SLC6A2 (0.38) | KDM4ESLC6A2MAPTHK1HKDC1 | |
| SCHEMBL23385705 | 0.74 | KDM4E (0.38) | KDM4EHPGDMAPTNPSR1TDP1 | |
| SCHEMBL23385708 | 0.74 | KDM4E (0.38) | KDM4EHPGDMAPTNPSR1TDP1 | |
| SCHEMBL23385706 | 0.74 | KDM4E (0.38) | KDM4EHPGDMAPTNPSR1TDP1 | |
| SCHEMBL26017048 | 0.70 | KIF11 (0.52) | HPGDMAPTNPC1RAB9AKIF11 | |
| SCHEMBL23386030 | 0.69 | HPGD (0.41) | KDM4EHPGDMAPTNPC1RAB9A | |
| SCHEMBL548066 | 0.68 | TSHR (0.50) | HPGDMAPTNPC1RAB9AKIF11 | |
| SCHEMBL23385753 | 0.68 | BRD4 (0.36) | KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220395821-A1 | COVALENT ORGANIC FRAMEWORKS AND APPLICATIONS AS PHOTOCATALYSTS | UNIV SOUTH FLORIDA (US) | 2022-12-15 | — | — | US | disclosed |