Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480261 | 1.00 | MAOA (0.40) | MAOAMAOBKDM1ACYP3A4CYP2D6 | |
| SCHEMBL5794231 | 0.79 | TAAR1 (0.55) | MAOAMAOBKDM1ACYP3A4CYP2D6 | |
| SCHEMBL3172135 | 0.78 | GRIN1 (0.52) | MAOAMAOBKDM1ACYP3A4CYP2D6 | |
| SCHEMBL2474613 | 0.78 | CYP1A2 (0.53) | MAOAMAOBKDM1ACYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL3650965 | 0.77 | TAAR1 (0.58) | MAOAMAOBKDM1ACYP3A4CYP2D6 | |
| SCHEMBL20525309 | 0.74 | GBA1 (0.45) | MAOAMAOBKDM1ACYP3A4CYP2D6 | |
| SCHEMBL17881888 | 0.74 | GBA1 (0.45) | MAOAMAOBKDM1ACYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL9529870 | 0.72 | GRIN1 (0.42) | MAOAMAOBKDM1ACYP3A4CYP2D6 | |
| SCHEMBL2477319 | 0.71 | CYP1A2 (0.57) | MAOAMAOBKDM1ACYP3A4CYP2D6 | |
| SCHEMBL27790005 | 0.69 | CYP3A4 (0.50) | MAOAMAOBCYP3A4CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2388245-B1 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | PIRAMAL IMAGING SA (CH) | 2017-07-12 | — | — | EP | claimed |
| EP-2374779-A1 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | Bayer Pharma Aktiengesellschaft (DE) | 2011-10-12 | — | — | EP | disclosed |