Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 10/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | IGLV6-57 | P01721 | 3/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 5/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 5/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | NR1D1 | P20393 | 3/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591460 | 0.89 | KCNA5 (0.40) | KCNA5IGLV6-57KCNJ5KCNJ3HDAC3 | |
| SCHEMBL21591520 | 0.86 | HDAC3 (0.41) | KCNA5IGLV6-57KCNJ5KCNJ3HDAC3 | |
| SCHEMBL21591555 | 0.83 | KCNA5 (0.40) | KCNA5IGLV6-57KCNJ5KCNJ3HDAC3 | |
| SCHEMBL21592245 | 0.83 | KCNA5 (0.38) | KCNA5IGLV6-57KCNJ5KCNJ3HDAC3 | |
| SCHEMBL21592279 | 0.83 | KCNA5 (0.44) | KCNA5IGLV6-57KCNJ5KCNJ3HDAC3 | |
| SCHEMBL21591526 | 0.83 | PDE3B (0.39) | KCNA5IGLV6-57KCNJ5KCNJ3HDAC3 | |
| SCHEMBL21591552 | 0.82 | KCNA5 (0.41) | KCNA5IGLV6-57KCNJ5KCNJ3HDAC3 | |
| SCHEMBL21591564 | 0.78 | GPR119 (0.37) | KCNA5IGLV6-57KCNJ5KCNJ3 | |
| SCHEMBL21591500 | 0.77 | HDAC3 (0.41) | KCNA5IGLV6-57KCNJ5KCNJ3HDAC3 | |
| SCHEMBL31361801 | 0.77 | HDAC3 (0.41) | KCNA5IGLV6-57KCNJ5KCNJ3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12162863-B2 | Modulators of stimulator of interferon genes (STING) | Ryvu Therapeutics S.A. (PL) | 2024-12-10 | — | — | US | disclosed |
| US-20220402898-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2022-12-22 | — | — | US | disclosed |
| US-20220402898-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12162863-B2 | Modulators of stimulator of interferon genes (STING) | STING1, IRF3, CGAS | KCNA5 2592/4885KCNJ1 2137/4885IGLV6-57 2946/4885 |
| US-20220402898-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | STING1, IRF3, CGAS | KCNA5 2592/4885KCNJ1 2137/4885IGLV6-57 2946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.