Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 18/20 | 0.43 |
| ▸ | HTR2A | P28223 | 15/20 | 0.43 |
| ▸ | HTR2B | P41595 | 14/20 | 0.43 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244683 | 1.00 | HTR2C (0.43) | HTR2CHTR2AHTR2BTIPARP | |
| SCHEMBL31244734 | 0.87 | HTR2C (0.47) | HTR2CHTR2AHTR2BTIPARP | |
| SCHEMBL31244842 | 0.87 | HTR2C (0.47) | HTR2CHTR2AHTR2BTIPARP | |
| SCHEMBL24640721 | 0.87 | HTR2C (0.47) | HTR2CHTR2AHTR2BTIPARP | |
| SCHEMBL26915008 | 0.84 | HTR2C (0.40) | HTR2CHTR2AHTR2B | |
| SCHEMBL24764605 | 0.84 | HTR2C (0.40) | HTR2CHTR2AHTR2B | |
| SCHEMBL29841692 | 0.84 | HTR2C (0.40) | HTR2CHTR2AHTR2B | |
| SCHEMBL24763872 | 0.82 | HTR2A (0.42) | HTR2CHTR2AHTR2B | |
| SCHEMBL31244645 | 0.82 | HTR2A (0.42) | HTR2CHTR2AHTR2B | |
| SCHEMBL31244740 | 0.82 | CHRNB2 (0.40) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184103-A1 | TRICYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 武汉誉祥医药科技有限公司 | 2022-09-09 | — | — | WO | disclosed |