Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL253526 | 0.77 | — | — | |
| SCHEMBL6114607 | 0.76 | ALDH1A1 (0.35) | — | |
| SCHEMBL166053 | 0.76 | FOLH1 (0.32) | FOLH1 | |
| SCHEMBL15532241 | 0.72 | — | — | |
| SCHEMBL16325091 | 0.71 | XPO1 (0.32) | — | |
| SCHEMBL7008079 | 0.70 | — | — | |
| SCHEMBL6781632 | 0.70 | — | — | |
| SCHEMBL20637706 | 0.70 | — | — | |
| Lithium Ion SCHEMBL31020254 | 0.68 | — | — | |
| SCHEMBL27596102 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858991-A2 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | Karyopharm Therapeutics, Inc. (US) | 2015-04-15 | — | — | EP | disclosed |
| WO-2014205393-A1 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | Karyopharm Therapeutics Inc. (US) | 2014-12-24 | — | — | WO | disclosed |
| EP-2736887-A1 | HYDRAZIDE CONTAINING NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | Karyopharm Therapeutics, Inc. (US) | 2014-06-04 | — | — | EP | disclosed |
| WO-2013170068-A2 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | KARYOPHARM THERAPEUTICS, INC. (US) | 2013-11-14 | — | — | WO | disclosed |
| WO-2013019548-A1 | HYDRAZIDE CONTAINING NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | KARYOPHARM THERAPEUTICS, INC. (US) | 2013-02-07 | — | — | WO | disclosed |
| EP-2542089-A1 | NUCLEAR TRANSPORT MODULATIORS AND USES THEREOF | Karyopharm Therapeutics, Inc. (US) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011109799-A1 | NUCLEAR TRANSPORT MODULATIORS AND USES THEREOF | KARYOPHARM THERAPEUTICS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |