Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.54 |
| ▸ | NMBR | P28336 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476429 | 1.00 | SIRT2 (0.54) | SIRT2NMBROPRK1PSEN1PSEN2 | |
| SCHEMBL2476149 | 0.86 | SIRT2 (0.52) | SIRT2NMBR | |
| SCHEMBL2476152 | 0.86 | SIRT2 (0.52) | SIRT2NMBR | |
| SCHEMBL2478687 | 0.83 | SIRT2 (0.51) | SIRT2NMBR | |
| SCHEMBL2472298 | 0.80 | SIRT2 (0.49) | SIRT2NMBR | |
| SCHEMBL2472296 | 0.80 | SIRT2 (0.49) | SIRT2NMBR | |
| SCHEMBL2472940 | 0.80 | SIRT2 (0.49) | SIRT2NMBR | |
| SCHEMBL21176255 | 0.78 | SIRT2 (0.67) | SIRT2NMBR | |
| SCHEMBL21176257 | 0.78 | SIRT2 (0.67) | SIRT2NMBR | |
| SCHEMBL2472392 | 0.78 | SIRT2 (0.51) | SIRT2NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371421-A1 | Ligands of insulin degrading enzyme and their uses | Université de Lille 2 Droit et Santé (FR) | 2011-10-05 | — | — | EP | disclosed |