Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.52 |
| ▸ | NMBR | P28336 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476152 | 1.00 | SIRT2 (0.52) | SIRT2NMBRPIN1 | |
| SCHEMBL2470124 | 0.88 | SIRT2 (0.64) | SIRT2NMBR | |
| SCHEMBL2470129 | 0.88 | SIRT2 (0.64) | SIRT2NMBR | |
| SCHEMBL2476429 | 0.86 | SIRT2 (0.54) | SIRT2NMBR | |
| SCHEMBL2476430 | 0.86 | SIRT2 (0.54) | SIRT2NMBR | |
| SCHEMBL2478687 | 0.83 | SIRT2 (0.51) | SIRT2NMBRPIN1 | |
| SCHEMBL27245496 | 0.80 | SIRT2 (0.50) | SIRT2NMBR | |
| SCHEMBL27245495 | 0.80 | SIRT2 (0.50) | SIRT2NMBR | |
| SCHEMBL14454002 | 0.80 | SIRT2 (0.57) | SIRT2NMBR | |
| SCHEMBL2472296 | 0.80 | SIRT2 (0.49) | SIRT2NMBRPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371421-A1 | Ligands of insulin degrading enzyme and their uses | Université de Lille 2 Droit et Santé (FR) | 2011-10-05 | — | — | EP | disclosed |
| EP-2371421-A1 | Ligands of insulin degrading enzyme and their uses | Université de Lille 2 Droit et Santé (FR) | 2011-10-05 | — | — | EP | disclosed |
| WO-2011107948-A2 | LIGANDS OF INSULIN DEGRADING ENZYME AND THEIR USES | UNIVERSITE LILLE 2 DROIT ET SANTE (FR) | 2011-09-09 | — | — | WO | disclosed |