Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2473783 | 0.86 | UTS2R (0.42) | UTS2RHDAC1EPHX2GAATSHR | |
| SCHEMBL2472961 | 0.82 | HDAC1 (0.55) | UTS2RHDAC1EPHX2HDAC3HDAC2 | |
| SCHEMBL2475487 | 0.81 | UTS2R (0.65) | UTS2RHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2473259 | 0.81 | UTS2R (0.51) | UTS2RHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2470960 | 0.80 | UTS2R (0.46) | UTS2RHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2478630 | 0.80 | HDAC1 (0.56) | UTS2RHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL3832758 | 0.80 | UTS2R (0.49) | UTS2RHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2474066 | 0.79 | HDAC1 (0.62) | UTS2RHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL3837712 | 0.78 | UTS2R (0.48) | UTS2RHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL3831092 | 0.78 | UTS2R (0.48) | UTS2RHDAC1HDAC3HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-B1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2011-10-12 | — | — | EP | disclosed |
| EP-2107052-A1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-10-07 | — | — | EP | disclosed |