Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | AHR | P35869 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10540728 | 0.92 | AHR (0.70) | HSD17B10CYP3A4TSHRALDH1A1TDP1 | |
| SCHEMBL1028691 | 0.88 | ESR2 (0.69) | HSD17B10CYP3A4TSHRALDH1A1TDP1 | |
| Formaldehyde SCHEMBL29255910 | 0.84 | ALOX5 (0.56) | HSD17B10CYP3A4TSHRALDH1A1TDP1 | |
| SCHEMBL28802584 | 0.82 | ALOX5 (0.68) | HSD17B10CYP3A4TSHRALDH1A1TDP1 | |
| SCHEMBL16296886 | 0.81 | ESR2 (0.60) | HSD17B10CYP3A4TSHRALDH1A1TDP1 | |
| SCHEMBL25712305 | 0.79 | MAP4K4 (0.47) | HSD17B10CYP3A4TSHRALDH1A1TDP1 | |
| SCHEMBL21848584 | 0.78 | AKT2 (0.46) | HSD17B10CYP3A4TSHRALDH1A1TDP1 | |
| SCHEMBL19553825 | 0.77 | HSD17B10 (1.00) | HSD17B10CYP3A4TSHRALDH1A1TDP1 | |
| SCHEMBL33883 | 0.77 | — | — | |
| SCHEMBL177878 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112358498-B | Tetraaryloxy IVB group binuclear metal complex and preparation and application thereof | 万华化学集团股份有限公司 | 2023-03-03 | — | — | CN | disclosed |
| EP-1348716-B1 | Aromatic polymer, method for producing the same and uses thereof | SUMITOMO CHEMICAL CO (JP) | 2011-10-12 | — | — | EP | disclosed |
| US-7285616-B2 | Aromatic polymer, method for producing the same and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-23 | — | — | US | disclosed |
| EP-1348716-A1 | Aromatic polymer, method for producing the same and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-10-01 | — | — | EP | disclosed |
| US-20030180596-A1 | Aromatic polymer, method for producing the same and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-09-25 | — | — | US | disclosed |