SCHEMBL2476526

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2478742	0.91	STAT6 (0.57)	MAPK10MAPK9STAT6SYKJAK3
	SCHEMBL2479159	0.90	STAT6 (0.58)	MAPK10MAPK9STAT6JAK3IRAK4
	SCHEMBL2482391	0.90	MAPK10 (0.60)	MAPK10MAPK9STAT6SYKJAK3
	SCHEMBL2479544	0.89	STAT6 (0.55)	MAPK10MAPK9STAT6SYKJAK3
	SCHEMBL2481818	0.88	STAT6 (0.72)	MAPK10MAPK9STAT6JAK3IRAK4
	SCHEMBL12301484	0.88	STAT6 (0.55)	MAPK10MAPK9STAT6SYKJAK3
	SCHEMBL12301469	0.86	STAT6 (0.64)	MAPK10MAPK9STAT6JAK3IRAK4
	SCHEMBL2478938	0.85	STAT6 (0.61)	MAPK10MAPK9STAT6SYKJAK3
	SCHEMBL2486601	0.84	STAT6 (0.60)	MAPK10MAPK9STAT6JAK3IRAK4
	SCHEMBL12301737	0.83	STAT6 (0.58)	STAT6SYKJAK3IRAK4JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.