Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24765900 | 1.00 | TAAR1 (0.53) | TAAR1HTR2AHTR1AHTR2CHTR2B | |
| SCHEMBL24765657 | 0.92 | TAAR1 (0.46) | TAAR1HTR2AHTR1AHTR2CHTR2B | |
| SCHEMBL24765658 | 0.92 | TAAR1 (0.46) | TAAR1HTR2AHTR1AHTR2CHTR2B | |
| SCHEMBL24765650 | 0.87 | TAAR1 (0.39) | TAAR1HTR2A | |
| SCHEMBL11739911 | 0.86 | TAAR1 (0.71) | TAAR1HTR2AHTR1AHTR2CHTR2B | |
| SCHEMBL31498057 | 0.86 | TAAR1 (0.71) | TAAR1HTR2AHTR1AHTR2CHTR2B | |
| SCHEMBL27878290 | 0.84 | TAAR1 (0.54) | TAAR1HTR2AHTR1AHTR2CHTR2B | |
| SCHEMBL27002118 | 0.84 | TAAR1 (0.47) | TAAR1HTR2A | |
| SCHEMBL11614042 | 0.83 | TAAR1 (0.53) | TAAR1HTR2AHTR1AHTR2CHTR2B | |
| Dimoxamine SCHEMBL896149 | 0.83 | TAAR1 (0.54) | TAAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204323-A1 | NON-HALLUCINOGENIC ARIADNE ANALOGS FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-09-29 | — | — | WO | disclosed |
| WO-2022204323-A1 | NON-HALLUCINOGENIC ARIADNE ANALOGS FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-09-29 | — | — | WO | disclosed |