Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24765647 | 0.93 | HTR2A (0.50) | HTR2AHTR2C | |
| SCHEMBL24765654 | 0.93 | HTR2A (0.50) | HTR2AHTR2C | |
| SCHEMBL24765867 | 0.90 | HTR2A (0.35) | HTR2A | |
| SCHEMBL24765863 | 0.87 | HTR2A (0.34) | HTR2AHTR2C | |
| SCHEMBL24765899 | 0.84 | HTR2A (0.59) | HTR2AHTR2C | |
| SCHEMBL24765639 | 0.84 | HTR2A (0.59) | HTR2AHTR2C | |
| SCHEMBL24765871 | 0.83 | HTR2A (0.40) | HTR2AHTR2C | |
| SCHEMBL24765865 | 0.83 | TAAR1 (0.42) | HTR2AHTR2C | |
| SCHEMBL24765861 | 0.82 | HTR2A (0.39) | HTR2AHTR2C | |
| SCHEMBL24765870 | 0.82 | TAAR1 (0.41) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204323-A1 | NON-HALLUCINOGENIC ARIADNE ANALOGS FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-09-29 | — | — | WO | disclosed |