Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 7/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24765861 | 0.95 | HTR2A (0.39) | TAAR1HTR2AHTR1AHTR2CHTR2B | |
| SCHEMBL24765863 | 0.95 | HTR2A (0.34) | TAAR1HTR2AHTR1AHTR2CHTR2B | |
| SCHEMBL24765901 | 0.92 | HTR2A (0.46) | TAAR1HTR2AHTR1AHTR2CHTR2B | |
| SCHEMBL24765640 | 0.92 | HTR2A (0.46) | TAAR1HTR2AHTR1AHTR2CHTR2B | |
| SCHEMBL24765647 | 0.90 | HTR2A (0.50) | TAAR1HTR2AHTR2C | |
| SCHEMBL24765865 | 0.88 | TAAR1 (0.42) | TAAR1HTR2AHTR2C | |
| SCHEMBL24765654 | 0.84 | HTR2A (0.50) | TAAR1HTR2AHTR2C | |
| SCHEMBL24765871 | 0.83 | HTR2A (0.40) | TAAR1HTR2AHTR2C | |
| SCHEMBL24765649 | 0.82 | HTR2A (0.40) | HTR2AHTR2C | |
| SCHEMBL24765867 | 0.81 | HTR2A (0.35) | TAAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204323-A1 | NON-HALLUCINOGENIC ARIADNE ANALOGS FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-09-29 | — | — | WO | disclosed |