SCHEMBL24765749

SCHEMBL24765749

c1ccc(-c2cccc3[nH]c4ccc(-c5ccc6c(c5)c5ccc7ccccc7c5n6-c5ccccc5)cc4c23)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 11/20 0.45
CCND1 P24385 11/20 0.45
ALK Q9UM73 3/20 0.40
CCNB2 O95067 1/20 0.39
CCNE2 O96020 1/20 0.39
CDK1 P06493 1/20 0.39
CCNB1 P14635 1/20 0.39
CCNE1 P24864 1/20 0.39
CDK2 P24941 1/20 0.39
CCNB3 Q8WWL7 1/20 0.39
TLR9 Q9NR96 1/20 0.34
TLR8 Q9NR97 1/20 0.34
TLR7 Q9NYK1 1/20 0.34
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19203100 0.87 KIF11 (0.39) CDK4CCND1GABRPGABRDGABRA1
SCHEMBL19213873 0.85 CDK4 (0.41) CDK4CCND1ALKTLR9TLR8
SCHEMBL24766053 0.85 CDK4 (0.43) CDK4CCND1ALKGABRPGABRD
SCHEMBL19213876 0.85 KIF11 (0.39) CDK4CCND1
SCHEMBL19450255 0.81 CDK4 (0.51) CDK4CCND1ALKCCNB2CCNE2
SCHEMBL26492161 0.80 CDK4 (0.40) CDK4CCND1ALKCCNB2CCNE2
SCHEMBL28475639 0.80 CDK4 (0.44) CDK4CCND1ALKCCNB2CCNE2
SCHEMBL14979601 0.79 CDK4 (0.51) CDK4CCND1ALKCCNB2CCNE2
SCHEMBL24519185 0.79 CDK4 (0.41) CDK4CCND1CCNB2CCNE2CDK1
SCHEMBL17341522 0.79 TLR4 (0.34) HPGDMAPK1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022260443-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2022-12-15 WO disclosed