Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 7/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23647913 | 0.79 | — | — | |
| SCHEMBL23647820 | 0.77 | DRD4 (0.32) | DRD4 | |
| SCHEMBL23647727 | 0.76 | — | — | |
| SCHEMBL21624384 | 0.76 | — | — | |
| SCHEMBL30006207 | 0.76 | — | — | |
| SCHEMBL21624111 | 0.73 | CYP11B1 (0.31) | CYP11B2CYP11B1 | |
| SCHEMBL21624388 | 0.73 | — | — | |
| SCHEMBL30006774 | 0.73 | — | — | |
| SCHEMBL21624375 | 0.73 | CYP11B1 (0.30) | CYP11B2CYP11B1 | |
| SCHEMBL30006836 | 0.73 | CYP11B1 (0.30) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220396578-A1 | QUINOXALINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2022-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220396578-A1 | QUINOXALINE DERIVATIVES | NR3C1, NR3C2, GRK5 | CYP11B2 5/4885CYP11B1 7/4885DRD4 1593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.