Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 3/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17281237 | 0.83 | CNR1 (0.39) | ALDH1A1LMNACNR1CNR2CYP2C9 | |
| SCHEMBL29202717 | 0.80 | CNR1 (0.37) | ALDH1A1LMNACNR1CNR2CYP2C9 | |
| SCHEMBL30322363 | 0.80 | CNR1 (0.37) | ALDH1A1LMNACNR1CNR2CYP2C9 | |
| SCHEMBL14634345 | 0.80 | GRM5 (0.47) | ALDH1A1LMNACNR1CNR2CYP2C9 | |
| SCHEMBL28593194 | 0.72 | S1PR4 (0.40) | ALDH1A1LMNACNR1CNR2S1PR4 | |
| SCHEMBL23345398 | 0.70 | EGFR (0.43) | ALDH1A1LMNACNR1CNR2 | |
| SCHEMBL946380 | 0.69 | P2RX7 (0.50) | ALDH1A1CYP2C9CYP2C19GRM5HPGDS | |
| SCHEMBL32315381 | 0.69 | P2RX7 (0.50) | ALDH1A1CYP2C9CYP2C19GRM5HPGDS | |
| SCHEMBL22866604 | 0.69 | CNR1 (0.44) | ALDH1A1LMNACNR1CNR2CYP2C9 | |
| SCHEMBL264062 | 0.68 | ATR (0.44) | NPSR1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4104865-A1 | ANTI-EGFR ANTIBODY DRUG CONJUGATES | AbbVie Inc. (US) | 2022-12-21 | — | — | EP | disclosed |