Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2510094 | 0.87 | KMT2A (0.44) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL2505165 | 0.86 | KMT2A (0.45) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL2480077 | 0.86 | KMT2A (0.43) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL2480096 | 0.86 | PDCD1 (0.41) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL2484142 | 0.86 | MAPT (0.41) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL2483580 | 0.84 | L3MBTL1 (0.47) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL2481856 | 0.83 | PPARG (0.43) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL2510942 | 0.83 | KMT2A (0.41) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL2503627 | 0.82 | MAPT (0.47) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL2481146 | 0.81 | KMT2A (0.40) | MAPTLMNAPOLBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8604235-B2 | Production of substituted phenylene aromatic diesters and compositions | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-10 | — | — | US | disclosed |
| EP-2376423-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | Dow Global Technologies LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010078519-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-08 | — | — | WO | disclosed |