Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 8/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2473466 | 0.93 | HDAC1 (0.61) | HDAC3PIK3CAHDAC1HDAC2HDAC4 | |
| SCHEMBL2478730 | 0.92 | HDAC1 (0.49) | HDAC3PIK3CAHDAC1HDAC2HDAC4 | |
| SCHEMBL4390020 | 0.91 | PIK3CA (0.48) | HDAC3PIK3CAHDAC1HDAC2HDAC4 | |
| SCHEMBL3833732 | 0.90 | HDAC1 (0.51) | HDAC3PIK3CAHDAC1HDAC2HDAC4 | |
| SCHEMBL2477952 | 0.90 | HDAC3 (0.47) | HDAC3PIK3CAHDAC1HDAC2HDAC4 | |
| SCHEMBL2474116 | 0.89 | HDAC1 (0.48) | HDAC3PIK3CAHDAC1HDAC2HDAC4 | |
| SCHEMBL4388408 | 0.88 | HDAC1 (0.54) | HDAC3PIK3CAHDAC1HDAC2HDAC4 | |
| SCHEMBL2473928 | 0.88 | HDAC1 (0.47) | HDAC3PIK3CAHDAC1HDAC2HDAC4 | |
| SCHEMBL2474349 | 0.88 | EGFR (0.49) | HDAC3PIK3CAHDAC1HDAC2HDAC4 | |
| SCHEMBL2473979 | 0.88 | HDAC1 (0.47) | HDAC3PIK3CAHDAC1HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-B1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2011-10-12 | — | — | EP | claimed |