Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BCL3 | P20749 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476882 | 0.92 | HDAC3 (0.51) | HDAC1HDAC3PIK3CAHDAC2HDAC4 | |
| SCHEMBL2473466 | 0.90 | HDAC1 (0.61) | HDAC1HDAC3PIK3CAHDAC2HDAC4 | |
| SCHEMBL4390020 | 0.90 | PIK3CA (0.48) | HDAC1HDAC3PIK3CAHDAC2HDAC4 | |
| SCHEMBL4392742 | 0.89 | HDAC1 (0.56) | HDAC1HDAC3PIK3CASMN1; SMN2HDAC2 | |
| SCHEMBL4396311 | 0.89 | HDAC1 (0.50) | HDAC1HDAC3PIK3CASMN1; SMN2HDAC2 | |
| SCHEMBL2477952 | 0.88 | HDAC3 (0.47) | HDAC1HDAC3PIK3CAHDAC2HDAC4 | |
| SCHEMBL2477122 | 0.88 | HDAC1 (0.56) | HDAC1HDAC3PIK3CASMN1; SMN2EPHX2 | |
| SCHEMBL3833732 | 0.88 | HDAC1 (0.51) | HDAC1HDAC3PIK3CAMAPK1HDAC2 | |
| SCHEMBL2473928 | 0.87 | HDAC1 (0.47) | HDAC1HDAC3PIK3CAHDAC2HDAC4 | |
| SCHEMBL2473979 | 0.87 | HDAC1 (0.47) | HDAC1HDAC3PIK3CAMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-B1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2011-10-12 | — | — | EP | disclosed |