Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.45 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2473878 | 0.95 | KCNH2 (0.49) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1375976 | 0.82 | KCNH2 (0.67) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1375415 | 0.82 | KCNH2 (0.67) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1375413 | 0.82 | KCNH2 (0.67) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1375971 | 0.82 | KCNH2 (0.67) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1375418 | 0.77 | KCNH2 (0.74) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1374736 | 0.77 | KCNH2 (0.74) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1374732 | 0.77 | KCNH2 (0.74) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1375424 | 0.77 | KCNH2 (0.74) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1375472 | 0.77 | KCNH2 (0.74) | KCNH2KCNQ1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370444-A1 | [4- (1-AMINO-ETHYL) -CYCLOHEXYL]-METHYL-AMINES AS ANTIBACTERIALS | AstraZeneca AB (SE) | 2011-10-05 | — | — | EP | disclosed |