Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 15/20 | 0.74 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.74 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1374732 | 1.00 | KCNH2 (0.74) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1375472 | 1.00 | KCNH2 (0.74) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1374736 | 1.00 | KCNH2 (0.74) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1375424 | 1.00 | KCNH2 (0.74) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1375415 | 0.95 | KCNH2 (0.67) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1375413 | 0.95 | KCNH2 (0.67) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1375976 | 0.95 | KCNH2 (0.67) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1375971 | 0.95 | KCNH2 (0.67) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1606428 | 0.91 | KCNH2 (0.62) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL1606427 | 0.91 | KCNH2 (0.62) | KCNH2KCNQ1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288084-A1 | [4-( 1-AMINO-ETHYL) - CYCLOHEXYL ] - METHYL - AMINES AS ANTIBACTERIALS | ASTRAZENECA AB (SE) | 2011-11-24 | — | — | US | disclosed |
| US-20110288084-A1 | [4-( 1-AMINO-ETHYL) - CYCLOHEXYL ] - METHYL - AMINES AS ANTIBACTERIALS | ASTRAZENECA AB (SE) | 2011-11-24 | — | — | US | disclosed |
| WO-2010055348-A1 | [4- (1-AMINO-ETHYL) -CYCLOHEXYL] -METHYL-AMINES AS ANTIBACTERIALS | ASTRAZENECA AB (SE) | 2010-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288084-A1 | [4-( 1-AMINO-ETHYL) - CYCLOHEXYL ] - METHYL - AMINES AS ANTIBACTERIALS | AAAS, EEF1A1, ACMSD | KCNH2 469/4885KCNQ1 1108/4885CACNA1C 3080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.