Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25771142 | 0.78 | CYP1A2 (0.36) | MAPK1PGR | |
| SCHEMBL18250270 | 0.77 | MAPK1 (0.34) | GRM2MAPK1 | |
| SCHEMBL22013190 | 0.75 | KDM4E (0.34) | MAPK1PGR | |
| SCHEMBL19250992 | 0.75 | CYP1A2 (0.35) | MAPK1PGR | |
| SCHEMBL25465246 | 0.75 | CYP1A2 (0.35) | MAPK1PGR | |
| SCHEMBL15960686 | 0.75 | CYP1A2 (0.35) | MAPK1PGR | |
| SCHEMBL24665488 | 0.74 | CNR2 (0.33) | GRM2MAPK1 | |
| SCHEMBL23219802 | 0.72 | CYP1A2 (0.39) | — | |
| SCHEMBL20374380 | 0.72 | CYP1A2 (0.39) | — | |
| SCHEMBL25867967 | 0.70 | COMT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220389007-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2022-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220389007-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | EIF2AK2, POLR2E, POLR2H | GRM2 4831/4885MAPK1 1795/4885PGR 3093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.