Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786786 | 1.00 | KCNJ1 (0.34) | KCNJ1LMNAALDH1A1 | |
| SCHEMBL21224353 | 0.84 | KCNJ1 (0.31) | KCNJ1LMNA | |
| SCHEMBL9939604 | 0.84 | KCNJ1 (0.31) | KCNJ1LMNA | |
| SCHEMBL17997112 | 0.81 | PRKDC (0.34) | LMNAALDH1A1 | |
| SCHEMBL27223306 | 0.79 | PDXK (0.43) | — | |
| SCHEMBL29187433 | 0.78 | KCNJ1 (0.33) | KCNJ1 | |
| SCHEMBL203480 | 0.78 | GRIN2D (0.38) | LMNAALDH1A1 | |
| SCHEMBL25302330 | 0.76 | KCNJ1 (0.33) | KCNJ1LMNA | |
| SCHEMBL3719916 | 0.74 | TRIM24 (0.35) | LMNAALDH1A1 | |
| SCHEMBL14484351 | 0.74 | KCNJ1 (0.36) | KCNJ1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500785-A | Azetidinyl-containing carboxylic acid compounds for the treatment of neurodegenerative diseases | 细胞基因公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2022266162-A1 | AZETIDINYL COMPOUNDS COMPRISING A CARBOXYLIC ACID GROUP FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | CELGENE CORPORATION (US) | 2022-12-22 | — | — | WO | disclosed |