SCHEMBL2477255

SCHEMBL2477255

Oc1ccc(-c2ccc(O)cc2Cl)c(Cl)c1

nearest known ligand 0.74

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 14/20 0.74
ESR2 Q92731 10/20 0.74
HSD17B10 Q99714 2/20 0.65
TTR P02766 1/20 0.54
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CYP3A4 P08684 1/20 0.48
HPGD P15428 1/20 0.48
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7903999 0.90 ESR1 (0.63) ESR1ESR2HSD17B10TTRCA12
SCHEMBL31190132 0.86 ESR1 (1.00) ESR1ESR2HSD17B10TTR
SCHEMBL3684267 0.85 ESR1 (0.70) ESR1ESR2HSD17B10
SCHEMBL9623591 0.85 ESR1 (0.57) ESR1ESR2HSD17B10TTRCA12
SCHEMBL30536550 0.83 ESR1 (0.55) ESR1ESR2HSD17B10TTRCA12
SCHEMBL2288038 0.81 ALOX5 (0.65) ESR1ESR2HSD17B10
SCHEMBL321960 0.81 ESR1 (0.53) ESR1ESR2HSD17B10CA12CA9
SCHEMBL5948912 0.79 ESR1 (0.52) ESR1ESR2HSD17B10TTRCYP3A4
SCHEMBL224868 0.79
SCHEMBL29374280 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1757634-B2 POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER USING SAME IDEMITSU KOSAN CO (JP) 2022-05-25 EP claimed
US-20250109219-A1 FLUOROELASTOMER CROSSLINKABLE COMPOSITION AND ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2025-04-03 US disclosed
EP-4506414-A1 COMPOSITION FOR FLUORINE RUBBER CROSSLINKING AND MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2025-02-12 EP disclosed
WO-2023195469-A1 COMPOSITION FOR FLUORINE RUBBER CROSSLINKING AND MOLDED ARTICLE ダイキン工業株式会社 2023-10-12 WO disclosed
EP-1757634-B2 POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER USING SAME IDEMITSU KOSAN CO (JP) 2022-05-25 EP disclosed
US-RE43604-E1 Polycarbonate resin and electrophotographic photosensitive member using same IDEMITSU KOSAN CO. LTD. (JP) 2012-08-28 US disclosed
EP-1757634-B1 POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER USING SAME IDEMITSU KOSAN CO (JP) 2012-06-06 EP disclosed
EP-1348716-B1 Aromatic polymer, method for producing the same and uses thereof SUMITOMO CHEMICAL CO (JP) 2011-10-12 EP disclosed
US-7491346-B2 Copolymerized 3,3'-dimethyl-4,4'-dihydroxybiphenyl and polysiloxane monomer and a solvent of methylene chloride; improved cleaning property, lubricity, abrasion resistance IDEMITSU KOSAN CO., LTD. (JP) 2009-02-17 US disclosed
US-20080146759-A1 Sulfur-Containing Compound, Method for Producing Same, Sulfur-Containing Polymer, and Optical Material IDEMITSU KOSAN CO., LTD (JP) 2008-06-19 US disclosed
EP-1274762-A1 POLYCARBONATE PREPARATION PROCESS THE DOW CHEMICAL COMPANY (US) 2003-01-15 EP disclosed
WO-2001077204-A1 POLYCARBONATE PREPARATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2001-10-18 WO disclosed
EP-0212944-B1 MELT-PROCESSABLE AROMATIC COPOLYESTER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-04-08 EP disclosed
EP-0383177-A2 Cross-linkable thermotropic liquid crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1990-08-22 EP disclosed
US-4746721-A ENGINEERING PLASTICS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1988-05-24 US disclosed
EP-0212944-A2 Melt-processable aromatic copolyester Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1987-03-04 EP disclosed
EP-0105090-A1 Polycarbonate composition GENERAL ELECTRIC COMPANY (US) 1984-04-11 EP disclosed
US-4366171-A Fungicidal biphenyl esters, mixtures thereof and method of use GAF CORPORATION (US) 1982-12-28 US disclosed
US-4358563-A MOLDING MATERIALS OF IMPROVED IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1982-11-09 US disclosed
US-4311824-A Thermotropic alkylaromatic copolyesters RHONE-POULENC INDUSTRIES (FR) 1982-01-19 US disclosed