Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 8/20 | 0.42 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 3/20 | 0.39 |
| ▸ | JAK3 | P52333 | 3/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.39 |
| ▸ | FLT3 | P36888 | 3/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24773714 | 0.91 | MAPT (0.41) | MAPTIGF1RBTKPKMYT1JAK2 | |
| SCHEMBL24773113 | 0.90 | MAPT (0.41) | MAPTIGF1RBTKPKMYT1 | |
| SCHEMBL24773079 | 0.90 | MAPT (0.40) | MAPTIGF1RPKMYT1JAK2JAK3 | |
| SCHEMBL24773900 | 0.90 | MAPT (0.43) | MAPTPKMYT1JAK2JAK3PTK2 | |
| SCHEMBL24773955 | 0.89 | PKMYT1 (0.40) | MAPTIGF1RPKMYT1 | |
| SCHEMBL24773088 | 0.88 | MAPT (0.39) | MAPTIGF1RBTKPKMYT1JAK2 | |
| SCHEMBL24773351 | 0.87 | MAPT (0.47) | MAPTIGF1RBTKPKMYT1JAK2 | |
| SCHEMBL24773067 | 0.87 | BTK (0.49) | BTKPKMYT1AXL | |
| SCHEMBL24773345 | 0.85 | WEE1 (0.45) | BTKPKMYT1JAK3EGFRAXL | |
| SCHEMBL24773141 | 0.84 | ALK (0.44) | IGF1RBTKJAK2JAK3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174796-A1 | PYRIMIDINE COMPOUND AS WEE-1 INHIBITOR | 微境生物医药科技(上海)有限公司 | 2022-08-25 | — | — | WO | disclosed |