Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.49 |
| ▸ | AXL | P30530 | 2/20 | 0.48 |
| ▸ | WEE1 | P30291 | 11/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24773345 | 0.97 | WEE1 (0.45) | BTKAXLWEE1SLC2A1PLK1 | |
| SCHEMBL24773062 | 0.95 | WEE1 (0.45) | BTKAXLWEE1SLC2A1PLK1 | |
| SCHEMBL24773141 | 0.92 | ALK (0.44) | BTKAXLWEE1SYKTNK2 | |
| SCHEMBL24773152 | 0.92 | BTK (0.51) | BTKAXLWEE1SYK | |
| SCHEMBL24773140 | 0.91 | TBK1 (0.43) | BTKAXLWEE1SYK | |
| SCHEMBL24773154 | 0.90 | AXL (0.46) | BTKAXLWEE1SLC2A1SYK | |
| SCHEMBL24773142 | 0.90 | AXL (0.42) | BTKAXLWEE1 | |
| SCHEMBL24773716 | 0.90 | WEE1 (0.44) | BTKAXLWEE1SLC2A1PLK1 | |
| SCHEMBL24773143 | 0.89 | WEE1 (0.42) | BTKWEE1SLC2A1PLK1SYK | |
| SCHEMBL24773146 | 0.89 | MAP3K14 (0.48) | BTKAXLWEE1SLC2A1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174796-A1 | PYRIMIDINE COMPOUND AS WEE-1 INHIBITOR | 微境生物医药科技(上海)有限公司 | 2022-08-25 | — | — | WO | disclosed |