Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 16/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474123 | 0.98 | TACR3 (0.53) | TACR3HSD11B1MEN1KMT2A | |
| SCHEMBL2477738 | 0.94 | TACR3 (0.53) | TACR3HSD11B1 | |
| SCHEMBL2477331 | 0.94 | TACR3 (0.58) | TACR3HSD11B1MEN1KMT2A | |
| SCHEMBL2478361 | 0.89 | TACR3 (0.52) | TACR3HSD11B1MEN1KMT2A | |
| SCHEMBL2480905 | 0.89 | TACR3 (0.51) | TACR3 | |
| SCHEMBL2476664 | 0.88 | TACR3 (0.58) | TACR3HSD11B1MEN1KMT2A | |
| SCHEMBL2474067 | 0.87 | TACR3 (0.51) | TACR3 | |
| SCHEMBL2477401 | 0.85 | TACR3 (0.44) | TACR3HSD11B1MEN1KMT2A | |
| SCHEMBL2480350 | 0.85 | TACR3 (0.67) | TACR3HSD11B1MEN1KMT2A | |
| SCHEMBL2477257 | 0.83 | TACR3 (0.54) | TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656349-B1 | CYCLOPROPYL DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2011-10-12 | — | — | EP | claimed |