Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 5/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476664 | 0.94 | TACR3 (0.58) | TACR3HSD11B1MEN1KMT2AALDH1A1 | |
| SCHEMBL2477328 | 0.94 | TACR3 (0.53) | TACR3HSD11B1MEN1KMT2A | |
| SCHEMBL2474123 | 0.92 | TACR3 (0.53) | TACR3HSD11B1MEN1KMT2A | |
| SCHEMBL2480350 | 0.90 | TACR3 (0.67) | TACR3HSD11B1MEN1KMT2ATACR2 | |
| SCHEMBL2477738 | 0.89 | TACR3 (0.53) | TACR3HSD11B1DRD2DRD4 | |
| SCHEMBL2480227 | 0.88 | OPRM1 (0.45) | TACR3OPRM1DRD2DRD4TACR2 | |
| SCHEMBL2480276 | 0.86 | TACR3 (0.54) | TACR3HSD11B1MEN1KMT2AALDH1A1 | |
| SCHEMBL2478361 | 0.85 | TACR3 (0.52) | TACR3HSD11B1MEN1KMT2ADRD2 | |
| SCHEMBL2477412 | 0.83 | TACR3 (0.60) | TACR3HSD11B1TACR2TACR1 | |
| SCHEMBL2479990 | 0.82 | TACR3 (0.46) | TACR3SMN1; SMN2DRD2DRD4TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656349-B1 | CYCLOPROPYL DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2011-10-12 | — | — | EP | claimed |