Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.47 |
| ▸ | CDK7 | P50613 | 3/20 | 0.47 |
| ▸ | CDK4 | P11802 | 3/20 | 0.47 |
| ▸ | FYN | P06241 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 2/20 | 0.47 |
| ▸ | RET | P07949 | 2/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | FLT3 | P36888 | 2/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.47 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | CDK9 | P50750 | 2/20 | 0.47 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.47 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24773089 | 0.92 | SLC2A1 (0.63) | SLC2A1PDGFRBCDK7CDK4FYN | |
| SCHEMBL24773361 | 0.85 | WEE1 (0.57) | SLC2A1PDGFRBCDK7CDK4FYN | |
| SCHEMBL24773121 | 0.83 | SLC2A1 (0.53) | SLC2A1CDK7FYNCSF1RRET | |
| SCHEMBL29310121 | 0.79 | SLC2A1 (0.59) | SLC2A1PDGFRBCDK7CDK4FYN | |
| SCHEMBL24773698 | 0.79 | BTK (0.54) | SLC2A1AURKAWEE1BTKTNK2 | |
| SCHEMBL30997614 | 0.79 | SLC2A1 (0.59) | SLC2A1PDGFRBCDK7CDK4FYN | |
| SCHEMBL30997622 | 0.77 | SLC2A1 (0.57) | SLC2A1PDGFRBCDK7CDK4FYN | |
| SCHEMBL29310117 | 0.77 | SLC2A1 (0.57) | SLC2A1PDGFRBCDK7CDK4FYN | |
| SCHEMBL24773713 | 0.76 | SLC2A1 (0.41) | SLC2A1CDK7CDK1CCNA2CDK2 | |
| SCHEMBL24773087 | 0.76 | WEE1 (0.58) | SLC2A1ALKWEE1JAK2PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174796-A1 | PYRIMIDINE COMPOUND AS WEE-1 INHIBITOR | 微境生物医药科技(上海)有限公司 | 2022-08-25 | — | — | WO | disclosed |