Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 13/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.57 |
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 5/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24773361 | 0.92 | WEE1 (0.57) | WEE1SLC2A1PLK1BRD4JAK2 | |
| SCHEMBL24773118 | 0.92 | WEE1 (0.51) | WEE1SLC2A1PLK1BRD4JAK2 | |
| SCHEMBL24773067 | 0.87 | BTK (0.49) | WEE1SLC2A1PLK1BRD4 | |
| SCHEMBL24773345 | 0.87 | WEE1 (0.45) | WEE1SLC2A1PLK1BRD4 | |
| SCHEMBL24773062 | 0.87 | WEE1 (0.45) | WEE1SLC2A1PLK1BRD4 | |
| SCHEMBL24773879 | 0.86 | PKMYT1 (0.47) | WEE1SLC2A1PLK1BRD4JAK2 | |
| SCHEMBL24773089 | 0.83 | SLC2A1 (0.63) | WEE1SLC2A1BRD4ALKJAK2 | |
| SCHEMBL24773716 | 0.83 | WEE1 (0.44) | WEE1SLC2A1PLK1BRD4 | |
| SCHEMBL24773143 | 0.83 | WEE1 (0.42) | WEE1SLC2A1PLK1BRD4 | |
| SCHEMBL24773417 | 0.83 | AXL (0.42) | WEE1SLC2A1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174796-A1 | PYRIMIDINE COMPOUND AS WEE-1 INHIBITOR | 微境生物医药科技(上海)有限公司 | 2022-08-25 | — | — | WO | disclosed |