Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | BLK | P51451 | 1/20 | 0.54 |
| ▸ | ITK | Q08881 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 3/20 | 0.48 |
| ▸ | CCNK | O75909 | 11/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 11/20 | 0.44 |
| ▸ | ATR | Q13535 | 2/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.43 |
| ▸ | CDK2 | P24941 | 4/20 | 0.43 |
| ▸ | CDK7 | P50613 | 4/20 | 0.43 |
| ▸ | CCNH | P51946 | 4/20 | 0.43 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.43 |
| ▸ | F13A1 | P00488 | 2/20 | 0.43 |
| ▸ | TGM1 | P22735 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22676597 | 0.84 | EGFR (0.50) | BTKEGFRSRCBLKITK | |
| SCHEMBL30303260 | 0.84 | EGFR (0.50) | BTKEGFRSRCBLKITK | |
| SCHEMBL22676646 | 0.82 | FGFR1 (0.53) | BTKEGFRSRCBLKITK | |
| SCHEMBL30303699 | 0.82 | FGFR1 (0.53) | BTKEGFRSRCBLKITK | |
| SCHEMBL22676808 | 0.81 | BTK (0.49) | BTKEGFRSRCBLKITK | |
| SCHEMBL25715673 | 0.80 | CDK2 (0.45) | BTKEGFRSRCBLKITK | |
| SCHEMBL22138109 | 0.80 | TGM2 (0.72) | BTKEGFRSRCBLKITK | |
| SCHEMBL14165308 | 0.79 | BTK (0.72) | BTKEGFRSRCBLKITK | |
| SCHEMBL22055544 | 0.79 | TGM2 (0.70) | BTKEGFRSRCBLKITK | |
| SCHEMBL29178719 | 0.78 | BTK (0.50) | BTKEGFRSRCBLKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022206939-A1 | HETEROCYCLIC COMPOUND SERVING AS FGFR INHIBITOR AND APPLICATION THEREOF | 海南耀臻生物医药科技有限公司 | 2022-10-06 | — | — | WO | disclosed |