Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.46 |
| ▸ | WEE1 | P30291 | 15/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24773103 | 0.96 | PKMYT1 (0.43) | PKMYT1SLC2A1WEE1PLK1 | |
| SCHEMBL24773994 | 0.96 | PKMYT1 (0.43) | PKMYT1SLC2A1WEE1PLK1 | |
| SCHEMBL24773406 | 0.92 | PKMYT1 (0.43) | PKMYT1SLC2A1WEE1PLK1 | |
| SCHEMBL24773988 | 0.91 | WEE1 (0.41) | PKMYT1SLC2A1WEE1PLK1 | |
| SCHEMBL24773876 | 0.91 | WEE1 (0.41) | PKMYT1SLC2A1WEE1PLK1 | |
| SCHEMBL24773716 | 0.90 | WEE1 (0.44) | SLC2A1WEE1PLK1BRD4 | |
| SCHEMBL24773417 | 0.90 | AXL (0.42) | SLC2A1WEE1PLK1 | |
| SCHEMBL24773872 | 0.90 | WEE1 (0.42) | SLC2A1WEE1PLK1 | |
| SCHEMBL24773117 | 0.90 | WEE1 (0.43) | SLC2A1WEE1PLK1 | |
| SCHEMBL24773870 | 0.89 | WEE1 (0.45) | PKMYT1SLC2A1WEE1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174796-A1 | PYRIMIDINE COMPOUND AS WEE-1 INHIBITOR | 微境生物医药科技(上海)有限公司 | 2022-08-25 | — | — | WO | disclosed |