Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 13/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CCNH | P51946 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24773417 | 0.92 | AXL (0.42) | WEE1SLC2A1BTKPLK1CCNT1 | |
| SCHEMBL24773117 | 0.92 | WEE1 (0.43) | WEE1SLC2A1BTKPLK1SYK | |
| SCHEMBL24773872 | 0.92 | WEE1 (0.42) | WEE1SLC2A1BTKPLK1CCNT1 | |
| SCHEMBL24773870 | 0.91 | WEE1 (0.45) | WEE1SLC2A1BTKPLK1CCNT1 | |
| SCHEMBL24773080 | 0.91 | WEE1 (0.45) | WEE1SLC2A1BTKPLK1SYK | |
| SCHEMBL24773061 | 0.90 | WEE1 (0.41) | WEE1SLC2A1BTKPLK1SYK | |
| SCHEMBL24773908 | 0.90 | PKMYT1 (0.45) | WEE1SLC2A1PLK1 | |
| SCHEMBL24773879 | 0.90 | PKMYT1 (0.47) | WEE1SLC2A1PLK1BRD4 | |
| SCHEMBL24773067 | 0.90 | BTK (0.49) | WEE1SLC2A1BTKPLK1BRD4 | |
| SCHEMBL24773999 | 0.90 | WEE1 (0.41) | WEE1SLC2A1BTKPLK1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174796-A1 | PYRIMIDINE COMPOUND AS WEE-1 INHIBITOR | 微境生物医药科技(上海)有限公司 | 2022-08-25 | — | — | WO | disclosed |