Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475715 | 1.00 | CNR2 (0.55) | CNR2CNR1ALDH1A1SMN1; SMN2TSHR | |
| Trifluoroacetic Acid SCHEMBL30345244 | 0.93 | CNR1 (0.49) | CNR2CNR1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL15743806 | 0.88 | CNR1 (0.51) | CNR2CNR1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL13570410 | 0.88 | CNR2 (0.53) | CNR2CNR1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL11227100 | 0.86 | ACE (0.50) | CNR2CNR1ALDH1A1SMN1; SMN2KDM2B | |
| SCHEMBL14664075 | 0.85 | CNR1 (0.48) | CNR2CNR1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL14828682 | 0.85 | CNR1 (0.48) | CNR2CNR1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL6787956 | 0.83 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2DGAT1CA2ITGB3 | |
| SCHEMBL6787964 | 0.83 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2DGAT1CA2ITGB3 | |
| SCHEMBL19688673 | 0.82 | CNR1 (0.46) | CNR2CNR1ALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8653054-B2 | 2-(N-substituted piperazinyl) steroid derivatives | UNIVERSITE LAVAL (CA) | 2014-02-18 | — | — | US | disclosed |
| US-20110312926-A1 | 2-(N-Substituted Piperazinyl) Steroid Derivatives | UNIVERSITE LAVAL (CA) | 2011-12-22 | — | — | US | disclosed |
| EP-2373674-A1 | 2-(N-SUBSTITUTED PIPERAZINYL) STEROID DERIVATIVES | Université Laval (CA) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010060215-A1 | 2-(N-SUBSTITUTED PIPERAZINYL) STEROID DERIVATIVES | UNIVERSITé LAVAL (CA) | 2010-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312926-A1 | 2-(N-Substituted Piperazinyl) Steroid Derivatives | NR5A1, HSD17B11, CYP17A1 | CNR2 1064/4885CNR1 784/4885ALDH1A1 556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.