Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425641 | 0.83 | GAA (0.53) | MEN1KMT2AGAAMAPTKCNQ3 | |
| SCHEMBL30031533 | 0.83 | GAA (0.53) | MEN1KMT2AGAAMAPTKCNQ3 | |
| SCHEMBL30640105 | 0.81 | POLQ (0.48) | POLQ | |
| SCHEMBL24769264 | 0.81 | POLQ (0.48) | POLQ | |
| SCHEMBL31160429 | 0.80 | ABL1 (0.38) | KMT2AGAAKCNQ3KCNQ2KDM4E | |
| SCHEMBL22717387 | 0.79 | SMN1; SMN2 (0.43) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL16782971 | 0.78 | CNR2 (0.43) | MAPTPOLQ | |
| SCHEMBL29416286 | 0.77 | KDM4E (0.49) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL977733 | 0.77 | KDM4E (0.49) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL28369496 | 0.76 | KDM4E (0.49) | MEN1KMT2AGAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253327-A1 | PREPARATION AND USE OF COMPOUND HAVING IMMUNOMODULATORY FUNCTION | 上海轶诺药业有限公司 | 2022-12-08 | — | — | WO | disclosed |
| CN-115433210-A | Preparation and application of compound with immunoregulation function | 上海轶诺药业有限公司 | 2022-12-06 | — | — | CN | disclosed |