Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 3/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31160319 | 0.82 | PPARG (0.31) | HTTKCNQ3KCNQ2CNR2POLQ | |
| SCHEMBL24774262 | 0.80 | MEN1 (0.41) | ABL1KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL425641 | 0.77 | GAA (0.53) | ABL1KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL30031533 | 0.77 | GAA (0.53) | ABL1KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL31160329 | 0.77 | LMNA (0.36) | KDM4EHTTNR4A2LMNAMAPK1 | |
| SCHEMBL3654468 | 0.72 | KCNQ3 (0.43) | KDM4EALDH1A1KCNQ3KCNQ2POLQ | |
| SCHEMBL29416286 | 0.72 | KDM4E (0.49) | ABL1KDM4EALDH1A1SMN1; SMN2NR4A2 | |
| SCHEMBL977733 | 0.72 | KDM4E (0.49) | ABL1KDM4EALDH1A1SMN1; SMN2NR4A2 | |
| SCHEMBL28369496 | 0.71 | KDM4E (0.49) | ABL1KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL24584511 | 0.71 | GABRP (0.42) | KDM4EALDH1A1LMNACHEK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658661-A1 | MACROCYCLIC AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | Yuhan Corporation (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024177359-A1 | MACROCYCLIC AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | YUHAN CORPORATION (KR) | 2024-08-29 | — | — | WO | disclosed |