Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA6 | P23280 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871405 | 0.92 | ACE2 (0.56) | ACE2CA12CA6CA7CA9 | |
| Ethylenediamine SCHEMBL9064149 | 0.85 | SMN1; SMN2 (0.38) | ALOX15TP53ANPEPERAP2SMN1; SMN2 | |
| SCHEMBL27698375 | 0.83 | ACE2 (0.40) | ACE2CA12CA6CA7CA9 | |
| SCHEMBL467886 | 0.82 | SMN1; SMN2 (0.41) | TDP1ALOX15TP53ANPEPERAP2 | |
| SCHEMBL11032753 | 0.80 | CXCR4 (0.44) | ALOX15ANPEPERAP2SMN1; SMN2HSD17B10 | |
| SCHEMBL4388203 | 0.79 | ACE2 (0.57) | ACE2CA12CA6CA7CA9 | |
| Trientine SCHEMBL9064137 | 0.79 | ACE2 (0.69) | ACE2CA12CA6CA7CA9 | |
| Trientine SCHEMBL10749311 | 0.79 | ACE2 (0.57) | ACE2CA12CA6CA7CA9 | |
| SCHEMBL600834 | 0.79 | ACE2 (0.69) | ACE2CA12CA6CA7CA9 | |
| SCHEMBL2138667 | 0.79 | ACE2 (0.69) | ACE2CA12CA6CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307338-B1 | MONOLITHIC EXPANDABLE STRUCTURES, METHODS OF MANUFACTURE AND COMPOSITE STRUCTURES | HENKEL LOCTITE CORP (US) | 2011-10-12 | — | — | EP | disclosed |
| EP-1307338-A4 | MONOLITHIC EXPANDABLE STRUCTURES, METHODS OF MANUFACTURE AND COMPOSITE STRUCTURES | HENKEL LOCTITE CORP (US) | 2004-08-04 | — | — | EP | disclosed |
| EP-1307338-A1 | MONOLITHIC EXPANDABLE STRUCTURES, METHODS OF MANUFACTURE AND COMPOSITE STRUCTURES | Henkel Loctite Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002007963-A1 | MONOLITHIC EXPANDABLE STRUCTURES, METHODS OF MANUFACTURE AND COMPOSITE STRUCTURES | DEXTER CORPORATION (US) | 2002-01-31 | — | — | WO | disclosed |