SCHEMBL24775804

SCHEMBL24775804

CCc1ccccc1-n1c2ccccc2c2cccc(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)c21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DUSP3 P51452 1/20 0.38
NPEPPS P55786 1/20 0.34
PTPN5 P54829 1/20 0.34
PPARG P37231 2/20 0.33
HSP90AA1 P07900 1/20 0.33
RORC P51449 2/20 0.32
ALDH1A1 P00352 2/20 0.32
PGR P06401 1/20 0.32
RORA P35398 1/20 0.32
RORB Q92753 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
ATM Q13315 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
PTAFR P25105 1/20 0.32
TRPA1 O75762 1/20 0.32
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24433572 0.89 DUSP3 (0.34) DUSP3PPARGRORCPTAFR
SCHEMBL26076105 0.86 BTK (0.34) DUSP3PPARGRXRARXRBPTAFR
SCHEMBL24848434 0.86 DUSP3 (0.33) DUSP3RORC
SCHEMBL24311511 0.85 ALKBH5 (0.40) DUSP3PPARGALDH1A1LMNAPTAFR
SCHEMBL25470256 0.85 DUSP3 (0.36) DUSP3PTPN5PPARGALDH1A1RXRA
SCHEMBL23203894 0.85 DUSP3 (0.36) DUSP3PPARGALDH1A1RXRARXRB
SCHEMBL25470254 0.85 DUSP3 (0.36) DUSP3PPARGALDH1A1RXRARXRB
SCHEMBL24703479 0.84 DUSP3 (0.36) DUSP3PPARGALDH1A1HPGDRXRA
SCHEMBL25028761 0.83 DUSP3 (0.43) DUSP3NPEPPSALDH1A1LMNAHPGD
SCHEMBL23490981 0.82 DUSP3 (0.34) DUSP3PTPN5PPARGPTAFRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220396596-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220396596-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, DRD3 DUSP3 3778/4885NPEPPS 4375/4885PTPN5 4405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.