Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24775977 | 0.98 | CHRNA7 (0.37) | CHRNA7OPRM1OPRK1 | |
| SCHEMBL24775980 | 0.97 | CHRNA7 (0.38) | CHRNA7OPRM1OPRK1CHRNB2CHRNB4 | |
| SCHEMBL24775160 | 0.95 | CHRNA7 (0.39) | CHRNA7OPRM1OPRK1CHRNB2CHRNB4 | |
| SCHEMBL24775976 | 0.95 | CHRNA7 (0.39) | CHRNA7OPRM1OPRK1CHRNB2CHRNB4 | |
| SCHEMBL24775973 | 0.95 | CHRNA7 (0.39) | CHRNA7OPRM1OPRK1CHRNB2CHRNB4 | |
| SCHEMBL24775422 | 0.94 | OPRM1 (0.40) | CHRNA7OPRM1OPRK1 | |
| SCHEMBL24775423 | 0.92 | OPRM1 (0.39) | CHRNA7OPRM1OPRK1 | |
| SCHEMBL24775570 | 0.89 | CHRNA7 (0.39) | CHRNA7OPRM1OPRK1CHRNB2CHRNB4 | |
| SCHEMBL24775563 | 0.89 | CHRNA7 (0.39) | CHRNA7OPRM1OPRK1CHRNB2CHRNB4 | |
| SCHEMBL24775071 | 0.88 | HTR2C (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002369-A1 | Bcl-2 INHIBITORS | BEONE MEDICINES I GMBH (CH) | 2023-01-05 | — | — | US | disclosed |
| US-20220402915-A1 | BCL-2 INHIBITORS | BEONE MEDICINES I GMBH (CH) | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402915-A1 | BCL-2 INHIBITORS | BCL2, BCL2L1, BCL2L2 | CHRNA7 4831/4885OPRM1 4833/4885OPRK1 4318/4885 |
| US-20230002369-A1 | Bcl-2 INHIBITORS | BCL2, BCL2L1, BCL2L2 | CHRNA7 4831/4885OPRM1 4833/4885OPRK1 4318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.