Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23376620 | 0.81 | KMT2A (0.31) | KMT2A | |
| SCHEMBL9789201 | 0.80 | — | — | |
| SCHEMBL1218467 | 0.79 | PTGS2 (0.33) | PTGS1PTGS2 | |
| Hydrochloric Acid SCHEMBL23038345 | 0.79 | KMT2A (0.30) | KMT2A | |
| Hydrochloric Acid SCHEMBL9789372 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL6625509 | 0.78 | POLB (0.33) | PTGS1PTGS2 | |
| Hydrochloric Acid SCHEMBL1375002 | 0.78 | POLB (0.33) | PTGS1PTGS2 | |
| SCHEMBL2154186 | 0.78 | EPHX1 (0.33) | — | |
| SCHEMBL2360874 | 0.77 | ESR1 (0.33) | — | |
| SCHEMBL28949356 | 0.77 | CA12 (0.36) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011107948-A2 | LIGANDS OF INSULIN DEGRADING ENZYME AND THEIR USES | UNIVERSITE LILLE 2 DROIT ET SANTE (FR) | 2011-09-09 | — | — | WO | disclosed |