SCHEMBL24778792

SCHEMBL24778792

COC(=O)c1ccc(-c2ccc(OC(=O)c3ccc(OCCOCCOCCOC(=O)C(CC(C)C)C(C)C)cc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.50
▸ RAB9A P51151 1/20 0.46
▸ RARB P10826 2/20 0.42
▸ TDP1 Q9NUW8 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ SMN1; SMN2 Q16637 3/20 0.41
▸ KDM4E B2RXH2 2/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ HPGD P15428 1/20 0.41
▸ TAS1R3 Q7RTX0 1/20 0.40
▸ TAS1R1 Q7RTX1 1/20 0.40
▸ GAA P10253 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ ACR P10323 3/20 0.38
▸ HGFAC Q04756 1/20 0.38
▸ MTNR1A P48039 1/20 0.38
▸ MTNR1B P49286 1/20 0.38
▸ PRSS1 P07477 2/20 0.37
▸ POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22525442 0.94 RARB (0.42) MAPTRAB9ARARBSMN1; SMN2ALDH1A1
SCHEMBL21265969 0.94 RARB (0.42) MAPTRAB9ARARBSMN1; SMN2ALDH1A1
SCHEMBL22621671 0.92 RARB (0.53) MAPTRAB9ARARBSMN1; SMN2TSHR
SCHEMBL24969026 0.92 MAPT (0.45) MAPTRARBTDP1L3MBTL1SMN1; SMN2
SCHEMBL22621667 0.92 RARB (0.42) MAPTRARBTDP1L3MBTL1SMN1; SMN2
SCHEMBL25008908 0.92 KCNH2 (0.46) MAPTRARBTDP1L3MBTL1SMN1; SMN2
SCHEMBL24218379 0.91 APP (0.40) MAPTRAB9ARARBSMN1; SMN2TAS1R3
SCHEMBL24218382 0.91 PLK1 (0.44) MAPTRAB9ARARBSMN1; SMN2HPGD
SCHEMBL22621669 0.90 RARB (0.46) MAPTRARBTDP1L3MBTL1SMN1; SMN2
SCHEMBL24967734 0.89 MAPT (0.46) MAPTRARBSMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11860480-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2024-01-02 — — US disclosed
US-20230159827-A1 LIQUID CRYSTAL COMPOSITION, FLUORINE-CONTAINING POLYMER, OPTICALLY ANISOTROPIC LAYER, LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-05-25 — — US disclosed
US-20220389319-A1 LIQUID CRYSTAL COMPOSITION, LIGHT ABSORPTION ANISOTROPIC FILM, LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-12-08 — — US disclosed
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