SCHEMBL24967734

SCHEMBL24967734

CC(C)CC(C(=O)OCCOCCOCCOc1ccc(C(=O)Oc2ccc(-c3ccc(C#N)cc3)cc2)cc1)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ MMP2 P08253 8/20 0.42
▸ MMP3 P08254 6/20 0.41
▸ RARB P10826 2/20 0.40
▸ MMP1 P03956 1/20 0.40
▸ MMP9 P14780 1/20 0.40
▸ MMP13 P45452 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ TP53 P04637 1/20 0.38
▸ HDAC1 Q13547 1/20 0.38
▸ HDAC2 Q92769 1/20 0.38
▸ HRH2 P25021 1/20 0.38
▸ HRH1 P35367 1/20 0.38
▸ HRH3 Q9Y5N1 1/20 0.38
▸ ADRB2 P07550 1/20 0.38
▸ ADRB1 P08588 1/20 0.38
▸ ADRB3 P13945 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22621667 0.89 RARB (0.42) MAPTRARBSMN1; SMN2LMNAHRH3
SCHEMBL22525442 0.89 RARB (0.42) MAPTALDH1A1RARBSMN1; SMN2LMNA
SCHEMBL21265969 0.89 RARB (0.42) MAPTALDH1A1RARBSMN1; SMN2LMNA
SCHEMBL25008908 0.89 KCNH2 (0.46) MAPTRARBSMN1; SMN2LMNAHRH3
SCHEMBL22621671 0.89 RARB (0.53) MAPTRARBSMN1; SMN2TP53
SCHEMBL24778792 0.89 MAPT (0.50) MAPTALDH1A1RARBSMN1; SMN2LMNA
SCHEMBL24969026 0.89 MAPT (0.45) MAPTALDH1A1RARBSMN1; SMN2LMNA
SCHEMBL25793413 0.89 MAPT (0.47) MAPTALDH1A1MMP2MMP3RARB
SCHEMBL22525391 0.87 MAPT (0.45) MAPTALDH1A1MMP2MMP3RARB
SCHEMBL22621669 0.87 RARB (0.46) MAPTALDH1A1RARBSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11822180-B2 Polarizer and image display device FUJIFILM CORPORATION (JP) 2023-11-21 — — US disclosed
US-20230028750-A1 POLARIZER AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-01-26 — — US disclosed
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