Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 5/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2447600 | 0.88 | EGFR (0.37) | NR3C2SYKALOX5TP53THRB | |
| SCHEMBL2485548 | 0.73 | EGFR (0.38) | NR3C2SYKALOX5TP53THRB | |
| SCHEMBL2473812 | 0.72 | EGFR (0.37) | NR3C2SYKALOX5TP53THRB | |
| SCHEMBL2444446 | 0.70 | POLB (0.38) | — | |
| SCHEMBL2478896 | 0.69 | STAT6 (0.37) | NR3C2SYK | |
| SCHEMBL2448058 | 0.68 | GPBAR1 (0.37) | NR3C2SYK | |
| SCHEMBL2447045 | 0.68 | CREBBP (0.41) | SYK | |
| SCHEMBL8905497 | 0.68 | MAPT (0.46) | — | |
| SCHEMBL2483361 | 0.67 | ROCK2 (0.40) | NR3C2SYK | |
| SCHEMBL2446341 | 0.67 | ROCK2 (0.40) | SYKTP53EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367826-A1 | MODULATORS OF AMYLOID BETA. | AstraZeneca AB (SE) | 2011-09-28 | — | — | EP | disclosed |