Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25560652 | 0.85 | KCNJ1 (0.41) | CYP1A2CYP2D6CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL24135102 | 0.85 | EGLN2 (0.44) | CYP1A2CYP2D6CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL25442822 | 0.82 | L3MBTL1 (0.35) | CYP1A2CYP2D6KDM4EL3MBTL1HRH3 | |
| SCHEMBL6127814 | 0.79 | CYP2E1 (0.46) | CYP1A2CYP2D6CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL10280811 | 0.77 | CYP1A2 (0.61) | CYP1A2CYP2D6CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL9925940 | 0.76 | CYP1A2 (0.41) | CYP1A2CYP2D6CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL28674063 | 0.76 | PSEN1 (0.48) | CYP1A2CYP2D6CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL22199018 | 0.76 | CYP2E1 (0.44) | CYP1A2CYP2D6CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL11962606 | 0.76 | CYP2E1 (0.44) | CYP1A2CYP2D6CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL30445326 | 0.75 | KCNJ1 (0.49) | CYP1A2CYP2D6CYP3A4CYP19A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220396631-A1 | TRISPECIFIC BINDING MOLECULES AGAINST BCMA AND USES THEREOF | NOVARTIS AG (CH) | 2022-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220396631-A1 | TRISPECIFIC BINDING MOLECULES AGAINST BCMA AND USES THEREOF | CD2, CD2BP2, CD22 | CYP1A2 4664/4885CYP2D6 2632/4885CYP3A4 3551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.